Filiform papillae do not have taste buds.

نویسندگان

  • Mehmet Fatih Sönmez
  • Esra Balcioglu
  • Saim Ozdamar
  • Birkan Yakan
چکیده

1 Professor Assistente (Palestrante). 2 Mestrado (Assistente). 3 Professor (Palestrante). Endereço para correspondência: Mehmet Fatih Sönmez. Department of Histology and Embryology, Faculty of Medicine, Erciyes University, 38039 Kayseri, Turkey. Tel: (+90) 352 4374901 x 23356. Fax: (+90) 352 4375285 Este artigo foi submetido no SGP (Sistema de Gestão de Publicações) da BJORL em 17 de dezembro de 2007. cod. 5631. Artigo aceito em 7 de março de 2008. LETTER TO THE EDITOR Braz J Otorhinolaryngol. 2012;78(4):7.

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Neural control of ectopic filiform spines in adult tongue.

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Epithelial overexpression of BDNF or NT4 disrupts targeting of taste neurons that innervate the anterior tongue.

Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) are essential for the survival of geniculate ganglion neurons, which provide the sensory afferents for taste buds of the anterior tongue and palate. To determine how these target-derived growth factors regulate gustatory development, the taste system was examined in transgenic mice that overexpress BDNF (BDNF-OE) or NT4 (NT4-OE) ...

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Sox2 is required for development of taste bud sensory cells.

Sox2 is expressed in basal epithelial cells of the tongue, with high levels in taste bud placodes, fungiform papillae, and mature taste cells, and low levels in filiform papillae. High Sox2 expression appears to lie downstream from canonical Wnt signaling. In hypomorphic Sox2(EGFP/LP) embryos, placodes form but no mature taste buds develop. In contrast, transgenic overexpression of Sox2 in the ...

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عنوان ژورنال:
  • Brazilian journal of otorhinolaryngology

دوره 78 4  شماره 

صفحات  -

تاریخ انتشار 2012